Abstract: INTRODUCTION: DRPs was defined as events or circumstances that involves a patients drug treatment that actually or potentially interferes with the achievement of an optimal outcome. With respect to older patients with comorbidities and using multiple drugs, DRPs are associated with an increased risk of hospital readmissions, morbidity, and mortality. In Australia, an incidence of between 2.4% and 3.6% was found and in the US. DRPs include adverse drug reactions (ADRs), unnecessary drug therapy, untreated conditions, Wrong drug, and drug interactions and inappropriate choice of drugs.