Abstract: The incidence of oral cancer is increasing dramatically over the past years. According to National Cancer Registry Programme of Indian Council of Medical Research(ICMR), the mortality rate due to cancer has increased by approximately 6% between 2012 and 2014. The long term survival rates of oral cancer is less than 50%. Increased rate of morbidity and mortality is mainly due to the occurrence of multiple primary tumors and locally recurrent cancers. The concept of “field cancerization” by Slaughter et al. explains the mechanism by which second primary tumors develops. The presence of a ‘field’ with genetically altered cells appears to be a continuous risk factor for cancer. Detection and monitoring of these fields may have profound implications for cancer prevention. Here is a case report of “field cancerization” phenomenon.