Abstract: Fruit rot of brinjal caused by Phomopsis vexans is an important disease of eggplant inflicting heavy losses. The present investigation was carried out to test the efficacy of fungicides and two species of Trichoderma inhibiting the pathogen in vitro. Fungicides viz. Carbendazim (Bavistin 50% wp), Captaf (Captan-50 wp), Copperoxychloride (Blitox -50wp), Mancozeb (Dithane-75) and Ridomil MZ -72 were tested by poisoned food technique against brinjal fruit pathogen (Phomopsis vexans) in PDA medium. All the fungicides were significantly proved effective. Among them, Carbendazim at 0.1% showed complete inhibition of the mycelial growth of the pathogen. Among the two species of Trichoderma tested, T. viride was found to be most effective with 84% inhibition followed by T.harzianum 78.22 % inhibition respectively over control after 7th days of incubation.