Abstract: This paper examines the role that Greek Metropolitan Iakovos played in Albanian-Greek relations from the end of World War I to the establishment of a national Autocephalous Orthodox Albanian Church in 1922. As a result of the political and social structure that was in place during the Ottoman Empire, religion played a significant role in post-Ottoman politics. This was amplified in countries like Albania, where no national religious institutions existed. At the end of World War I, Greece used its influence towards the Patriarchate of Constantinople to increase its opportunity to annex the terra irredenta of Korçë and Gjirokastër, while Albania tried and managed to nationalize religious communities that existed in its territory.