Abstract: Tuberculosis is a crucial global public health problem which ranks second to HIV/AIDS as cause of mortality and is the leading cause of morbidity and mortality among people living with HIV/AIDS. Kenya is burdened with an estimated TB prevalence of 266 per 100,000. 52.5% of cases and 5.2% TB associated mortality occur among children below 5 years. Kisumu County is a TB and HIV endemic zone with a prevalence of 208-306 per 100,000 and 19.3% respectively. Children below 5 years who are household contacts with sputum positive pulmonary tuberculosis persons should be initiated on Isoniazid Preventive Therapy (IPT). This practice remains low hampering the ‘END TB’ strategies in Kisumu County.