Abstract: A field study was conducted at the Teaching and Research Farm, University of Agriculture, Makurdi in 2013 and 2014 cropping seasons. The objective was to determine the effects of variety and rate of poultry manure application on four varieties of cowpea viz: IT98K- 573 – 2 – 1, UAM 091056 – 2, UAM1046 – 6 – 2 and IT89KD – 391. The four varieties of cowpea and four rates of poultry manure: 0t/ha, 2t/ha, 4t/ha and 6t/ha constituted the treatments. Growth and yield parameters taken at 4, 6, and 8 weeks after planting and at harvest maturity included : plant height, number of leaves, pod length, number of pods per plant, number of seeds per plant, total dry matter yield, 100 seed weight and total seed yield. Results showed that varieties and rates of poultry manure exerted significant effects on the growth and yield of cowpea. Variety UAM 091046 -6 -2 produced the longest pod length, number of seeds per plant, 100 seed yield, number of pods per plant and total dry matter yield ; but IT98KD – 573-2-1 had the highest seed yield ( 837. 40 kg/ha ). The application of 2t/ha of poultry manure yielded the longest pod length , number of pods per plant , and number of seeds per plant ; while 4t/ha produced the highest total dry matter yield, 100 seed weight and seed yield. Results indicated that 4t/ha x IT98KD-573-2-1 interaction gave the highest seed yield ( 888.80kg/ha). Varieties UAM 091046-6-2 and IT98KD-573-2-1 showed greater potential for seed production than other varieties and should be adopted by farmers under Makurdi favourable weather conditions.