The exposure of ultraviolet and vitamin D serum levels have been linked to prostate cancer. At the cellular level, the main function of vitamin D is mediated by VDR in order to reduce proliferation and increase apoptosis in some malignancy. Objective: To assess the distribution of VDR immunohistochemical expression in prostate adenocarcinoma based on age, PSA value, and histopathological grading. Materials and Methods: This descriptive study with cross sectional approach used 34 samples from paraffin blocks from patients histopathologically diagnosed as prostate adenocarcinoma.
Zuhri Madriah, Delyuzar, Lidya Imelda Laksmi (2021); Immunohistochemical Expression of Vitamin D Receptor (VDR) In Prostate Adenocarcinoma in General Hospital Haji Adam Malik Medan in 2017-2018; International Journal of Scientific and Research Publications (IJSRP)
11(7) (ISSN: 2250-3153), DOI: http://dx.doi.org/10.29322/IJSRP.11.07.2021.p11558