Abstract: Santalum album commonly known as Sandalwood is used traditionally for health and wellness. It is an evergreen and hemi-parasitic tree and has a long history in Indian religious rituals and traditional Chinese medicine. Due to its wide application in cosmetics and therapeutics, we have done this study to explore the possibility of using aqueous extract of S. album from leaves and fruit for Phytochemical screening of these plants was performed for constituents indicated the presence of alkaloids, carbohydrates, tannin and phenolic compound, flavonoids, glycoside, amino acids, Inorganic acid and steroids. The results suggest that the Phytochemical properties of the leaf for using various ailments.