Abstract: Field experiments were conducted at the Teaching and Research Farm, University of Agriculture, Makurdi to determine the effect of fertilizer rates on soil chemical properties and yield of maize-soybean intercrop. The experimental design consisted of two factors: cropping system at two levels (sole and intercrops) and fertilizer rates at three levels (0, 150 and 300 kg/ha of NPK 20:10:10). The treatments were laid out in a Randomized Complete Block Design (RCBD) in a split plot arrangement and replicated three times. The cropping systems were assigned to the main plots while the fertilizer rates were in the sub plots. A composite soil sample was obtained from a plough layer (0-15 cm) at the beginning and at the end of the experiment according to the treatments and analyzed for particle size distribution, pH, organic carbon, total nitrogen, available phosphorus and exchangeable cations [Mg2+, Ca2+, Na+ and K+] as well as cation exchange capacity (CEC). Data collected for the yield parameters of maize and soybean for both cropping seasons were subjected to the Analysis of Variance (ANOVA) after which means were separated using Least Significant Difference (LSD) at P<0.05.