Abstract: Globally, postnatal period is crucial period in which most of the maternal and neonatal death occur due to wrong practice and knowledge most of which occur in developing country. The practice of postnatal care is increasing daily after proper knowledge and awareness on postnatal care. A research entitled “Knowledge and practice regarding Care of Postnatal Mother among the family care giver at Scheer Memorial Adventist Hospital, Banepa, Kavre” was conducted to assess the knowledge and practice of postnatal care.