Macro and micro morphological studies of root and stem of five Sida species, S. acuta, S. cordata, S. cordifolia, S. rhombifolia and S. schimperiana were carried out and compared, in order to determine the taxonomic relationship between them. Druses, hydropoten cells and trichomes occurred in all the species. Stomata are anisocytic. The foliar trichomes of Sida however possessed a remarkable diversity. Epidermal peeling of leaf shows biaxial trichomes. The foliar trichomes of Sida however possess a remarkable diversity such as peltate, stellate forked stalked and capitate trichomes. Much variation is noticed in anatomical characters of stem and root also.The present study provides the basic information and the interrelationship between the different plant species of Sida which are currently found in Kanyakumari district. The knowledge of taxonomy is a great tool for identification of the different plant species.