Abstract: Onchocerciasis has remained a public health problem, despite several efforts over the years to eliminate it both by the World Health Organization (WHO) and NGO’s. Prevalence of human onchocerciasis was conducted amongst 274 patients comprising 154 males and 120 females within the age range of 15 to 40 years and above, who were attending NKST Eye Care Programme at Mkar-Gboko, Benue State, Nigeria from January, 2012 through June, 2013. Onchocerciasis infection was diagnosed by parasitological observations for the presence of microfilariae of Onchocerca volvulus in skin biopsies using standard microscopy. A total of 37(13.50%) patients were found to be infected with Onchocerca volvulus, comprising 26(9.49%) males and 11(4.01%) females.