Abstract: Tuberculosis proves to be one of the most serious infections of the world with over 8.6m infections and 1.3m deaths recorded annually. Kenya is one of the 22 high TB burden countries and is ranked 13th according to the World Health Organization (WHO). The cost of treatment of tuberculosis is going up due to the emergent of drug resistant strains of mycobacterium tuberculosis. Multi drug resistant tuberculosis (MDR) and extensive drug resistant tuberculosis (XDR) are a complication of poor adherence to anti-tuberculosis medication. Despite several efforts to reduce worldwide prevalence of TB various factors hamper these efforts. One of the prominent factors affecting TB is adherence to anti-TB medication which is determined by several factors including drug availability, side effects, and cost associated to treatment and patient provider relationship. The aim of this study was to identify patient factors which influence adherence to anti-TB treatment among TB patients at Njoro Sub County Hospital.