Abstract: The basic objective of research is to investigate the factors which affect the profitability of the banks in Pakistan. In this study we investigate our factors to determine their impact on the profit. Data was collected from the 2003-2011. This period was used due to availability of data. Data is collected from the bank’s website and WDI. Total 17 of the banks were taken for this research. Panel data technique was used to measure the results of the fixed effect modal and random effect modal.