Abstract: Background: Globally, colorectal cancer(CRC) is the third most commonly diagnosed cancer in males and the second in females, with over 1.2 million new cases and 608,700 deaths estimated to have occurred in 2008. (1)Rates are substantially higher in males than in females. Globally, the incidence of CRC varies over 10-fold. The highest incidence rates are in Australia and New Zealand, Europe and North America, and the lowest rates are found in Africa and South-Central Asia. These geographic differences appear to be attributable to differences in dietary and environmental exposures that are imposed upon a background of genetically determined susceptibility. At our center, where head and neck, breast and cervical cancers predominate, rectal cancers make for a small percentage of malignancies. In between 2009 and 2013, out of a total of 4307 patients treated with radiotherapy, carcinoma rectum accounted for only 97 cases (2.2%).