Abstract: Hibiscus sabdarrifa L. extracts contain powerful antioxidants that can ameliorate Cadmium (Cd)-induced reproductive toxicity, though the active molecules responsible have not been categorically stated. This study is therefore aimed at exploring changes induced by H. sabdariffa L anthocyanins (HSA) in reproductive hormones of cadmium-exposed rats. Twenty four adult male wistar rats (185±5.2g) were randomly divided into four groups and where treated for 15 days: A: control, B: Cd alone, 3mg/kg b wt, C: HSA alone, 3mg/kg b wt, Group 4: HSA Pre-CD: HSA (3g/ kg b wt for ten consecutive days) and Cd (3mg/ kg b wt) for five days