Abstract: The present investigation deals with the phytochemical studies of leaves of different medicinal plants like Andrographis paniculata (Burm. f.) Wall ex Nees of the family Acanthaceae, Bauhinia acuminata Linn. of the family Caesalpiniaceae, Clerodendrum indicum (Linn.) O. Kuntze syn. C. siphonanthus R. Br. of the family Verbenaceae, Nerium odorum Soland. of the family Apocynaceae and Sida humilis Cav. Syn. S. veronicaefolia Lam., syn. S. cordata (Burm. f.) Borss. of the family Malvaceae. Methanolic (90%) extracts of leaf powders have been screened for qualitative determination of different secondary metabolites like starch, alkaloids, flavonoids, tannins, reducing sugars, amino acids and lignins by specific chemical color reaction tests.