ARCHANA MOON, DEEBA KHAN, PRANJALI GAJBHIYE & MONALI JARIYA
Drug resistance to therapeutic antibiotics pose a challenge to the identification of novel targets and drugs for the treatment of infectious diseases. Infections caused by Enterococcus faecalis are a major health problem. Moreover, among UTI causing enterococci, multi-drug resistant E. faecalis such as vancomycin-resistant strains (VRE) have been reported increasingly in many countries. SMX & TMP are the commonly prescribed inhibitors of DHFR & DHPS, the enzymes of the folate biosynthetic pathway. In this study, insilico docking of various ligands/inhibitors to the Enterococcus faecalis DHFR & DHPS proteins has been performed by using Autodock Suite, version 1.5 6rC2.
ARCHANA MOON, DEEBA KHAN, PRANJALI GAJBHIYE & MONALI JARIYA (2017); Insilico Docking of Various Inhibitors of E.Faecalis Folate Pathway;
Int J Sci Res Publ 7(3) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0317.php?rp=P636292