IJSRP, Volume 3, Issue 2, February 2013 Edition [ISSN 2250-3153]
Ruchee Khanna, Deepak Nayak M, Chethan Manohar, Sushma V.Belurkar, Akshatha N
Abstract:
Fibrin-ring granuloma (FRG) is characterized by a ring of fibrin and epithelioid histiocytes arranged around a central fat vacuole. It is classically described in Q fever. We report a case of FRG in the bone marrow biopsy of a 45-year old male with pancytopenia and clinical features of sepsis and bleeding diathesis. Serologically, the antibodies against Orientia tsutsugamushi were positive; being diagnostic of scrub typhus. The patient responded to specific antibiotics and supportive treatment. Thus, scrub typhus should be included as aetiology for FRG.