Abstract: Chronic Kidney Disease (CKD) has been reported as a major cause of death and nephrological disability in adults and it imposes a heavy emotional and financial burden on the family of the affected patient and society. The aim of the study was to determine the incidence of chronic kidney disease among patients in Owerri Zone, Imo State from January 2014 to December 2017. The study design was a retrospective survey on CKD cases and the data were collected from medical record cards with information on incidence rate and risk factors of CKD. The sampling technique adopted for this study was purposive sampling technique because the variables of interest were defined. The collected data were sorted and entered into computer software called Statistical Package for Social Science version 21.0.